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伴肠母细胞分化的胃腺癌并肝转移1例 被引量:1

Gastric adenocarcinoma with enteroblastic differentiation combined with liver metastasis: report of a case
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摘要 伴肠母细胞分化的胃腺癌合并绒毛膜癌成分并肝转移病例比较罕见。患者为65岁女性。胃癌根治标本, 胃肿瘤呈腺管状、乳头状结构, 细胞质透明, 诊断为伴肠母细胞分化的胃腺癌。在淋巴结转移灶和肝转移灶中出现了绒毛膜癌成分。免疫组织化学不同程度表达SALL4、Glypican3、甲胎蛋白、人绒毛膜促性腺激素、CDX2、CD10等抗体。二代测序提示TP53突变、MYC扩增等改变。此肿瘤恶性程度高, 预后差, 对术前化疗不敏感。患者术后12个月死亡。
作者 杜明占 郭凌川 王玉红 Du Mingzhan;Guo Lingchuan;Wang Yuhong(Department of Pathology,the First Affiliated Hospital of Soochow University,Suzhou 215006,China)
出处 《中华病理学杂志》 CAS CSCD 北大核心 2022年第8期768-770,共3页 Chinese Journal of Pathology
基金 国家自然科学基金(81902969) 苏州大学附属第一医院住院医师规范化培训研究课题(ZPKJ20210202)。
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