压力感受性反射激活疗法治疗心力衰竭的研究进展

Baroreflex Activation Therapy for Heart Failure

心力衰竭(HF)是多种心血管疾病终末阶段的共同表现,自主神经功能调节受损、交感-副交感失衡是其进展的重要因素。近年来研究表明,压力感受性反射激活疗法(BAT)通过植入设备发放电刺激颈动脉窦压力感受器,增强副交感系统兴奋性,抑制交感系统兴奋性,对HF起到治疗作用,改善患者预后。本文试对BAT治疗HF的相关研究及进展进行归纳与总结,并对其优势及应用前景进行综述与展望。

Heart failure(HF) is the endstage of multiple cardiovascular diseases.Impaired autonomic regulation and sympathetic-parasympathetic imbalance are considered key factors in HF progression.Baroreflex activation therapy(BAT),a novel device-based therapy which stimulates the carotid sinuses and regulates autonomic function, has demonstrated good efficacy in treating HF and improving prognosis.This review summarized the results of the latest relevant studies to provide support for further study of BAT.