摘要
INTRODUCTION Vitamin D3,also known as cholecalciferol,is a fat-soluble secosteroid whose key role in calcium and phosphate homeostasis and bone health has been recognized for long.In recent years,evidence has accumulated on multiple other biological effects,such as immunomodulatory and anti-inflammatory effects.The main source of vitamin D for humans is its production in the skin under sunlight exposure,which is often insufficient to ensure adequate vitamin D supply,particularly at high latitudes during fall,winter and spring.This editorial aims to draw attention to the underused potential of enhancing vitamin D3 supply for reducing cancer mortality and other adverse health outcomes,which might be a most valuable low-hanging fruit before,during and after the Coronavirus Disease 2019(COVID-19)pandemic.
