侵袭性在垂体腺瘤术后残留再生长与复发中的评价及临床现状

Evaluation and Current Clinical Progress of Invasiveness in Postoperative Residual Regrowth and Recurrence of Pituitary Adenoma

垂体腺瘤是颅内肿瘤中较常见的一种,约占颅内肿瘤的10%。垂体腺瘤虽然为良性肿瘤,但由于肿瘤侵袭性生长特性、设备条件和手术者技术有限等因素影响,使得肿瘤镜下全切和复发问题仍然较突出,复发垂体腺瘤比例逐年升高,治疗难度也随之增大。本文旨在总结本中心的侵袭性或复发性垂体腺瘤的病例资料,对复发性垂体腺瘤的诊治,包括再次经蝶手术适应证、手术技巧以及术后并发症的预防和处理等进行述评,为临床医师提供参考。

Pituitary adenoma is one common type of intracranial tumors,accounting for about 10%of intracranial tumors.Although pituitary adenomas are benign tumors,the complete resection and recurrence prevention remain challengeable due to aggressive growth of tumor,limited equipment conditions and surgical techniques of the surgeon.The proportion of recurrent pituitary adenomas is rising year by year and the difficulty of treatment also increases.This article reviews the diagnosis and treatment of recurrent pituitary adenomas based on the summary data of invasive or recurrent pituitary adenomas cases in our center,including indication for the second transsphenoidal surgery,surgical techniques,and prevention and treatment of postoperative complications,to provide reference for clinicians in this field.