冠状动脉CTA检查参数对自身冠脉血流动力学及脑梗塞的发生率的相关性研究

Correlation of Coronary Artery CTA Examination Parameters with Coronary Hemodynamics And Incidence of Cerebral Infarction

目的 探讨研究冠状动脉CTA检查参数对自身冠脉血流动力学及脑梗塞的发生率的相关性。方法 回顾性分析2017年12月至2019年7月于我院行冠状动脉CTA检查的152例患者资料,最终入选145例患者作为本次研究对象。对患者进行冠状动脉CTA检查,通过分析其检查参数与患者冠脉血流动力学及脑梗塞发生情况的相关性。结果 145例患者中共有162支冠状动脉血管进行了观察,其中血管的血流储备分数值在0.68~0.97,分数值超过0.80例数显著多于未超过0.80例数(P<0.05)。斑块长度、斑块总体积、脂质及纤维斑块体积等因素对血流动力学影响差异较大,具有统计学意义(P<0.05)。阳性指征环77条,阴性指征环89条,指征环阳性患者更易发生脑梗塞(P<0.05)。性别、年龄、血压及血糖水平可能影响患者脑梗塞发病率(P<0.05)。结论 冠状动脉CTA检查结果 中的斑块长度、总体积、脂质及纤维斑块体积等定量斑块参数为影响冠脉血流动力学的主要因素;显示的指征环与脑梗塞发病也有关联性,提示指征环为易损斑块的判断方法 ,也是脑梗塞高发风险的影像学标志。

Objective To investigate the correlation of corona ry artery CTA examination parameters with corona ry hemodynamics and incidence of cerebral infarction.Methods Data of 152 patients underwent coronary artery CTA exa mination in our hospital from December 2017 to July 2019 we re retrospectively analyzed,and a total of 145 patients were finally enrolled.Then the correlation between the examination parameters and the incidence of coronary hemodynamics and cerebral infa rction was analyzed.Results A total of 162 corona ry vessels were observed in 145 patients.The blood flow reserve values of blood vessels were 0.68-0.97,and the proportion of patients with value>0.80 was more than that of patients with value<0.80(P<0.05).The effects of plaque length,total plaque volume,lipid and fibrous plaque volume on hemodynamics were significantly different(P<0.05).There were 77 positive indications and 89 negative indications,and patients with positive indications were more likely to have cerebral infarction(P<0.05).Gender,age,blood pressure and blood glucose levels might affect the incidence of cerebral infarction(P<0.05).Conclusion Quantitative plaque parameters such as plaque length,total volume,lipid and fibrous plaque volume in coronary CTA results are the main factors affecting co ronary hemodynamics;moreover,the indications a re associated with the onset of ce rebral infra ction,indicating its diagnosis value for vulnerable plaque and cerebral infa rction.