新鲜血浆外敷在烧伤残余创面术前准备中的应用

External use of fresh frozen plasma in preoperative preparation of residual burn wound

目的观察新鲜冰冻血浆(FFP)外敷在烧伤残余创面术前准备中的应用效果。方法选取2017年5月—2021年5月中国人民解放军第九二二医院收治的52例烧伤残余创面患者,随机分为2组各26例,FFP组用新鲜血浆准备创面,NS组用生理盐水(Normal Saline,NS)准备创面。比较2组患者的创面床准备时间、细菌清除率、植皮存活率以及疼痛度。结果FFP组创面床准备时间短于NS组(P<0.05);治疗10 d后FFP组的细菌总清除率高于NS组(P<0.05);FFP组的植皮存活率高于NS组(P<0.05);FFP组疼痛度明显低于NS组(P<0.05)。结论应用新鲜冰冻血浆治疗烧伤残余创面可有效缩短创面床的准备时间,提高细菌清除率,提高植皮存活率,减轻患者的疼痛,具有良好的临床应用价值。

Objective To explore the clinical effect of external use of fresh frozen plasma in preoperative preparation of residual burn wound.Methods 52 patients with residual burn wound admitted to our hospital from May 2017 to May 2021 were divided into two groups randomly.26 patients were treated by the external use of FFP,and another 26 patients were treated by the external use of Normal Saline(NS).The wound bed preparation time,the bacterial clearance rates,survival rates of the skin graft and degree of pain were observed respectively.Results The wound bed preparation time of the FFP was shorter than NS group(P<0.05);FFP did better than NS in bacterial clearance rate after 10 days of treatment(P<0.05);FFP did better in the survival rates of the skin graft(P<0.05),and FFP experience less pain than NS group(P<0.05).Conclusion The external use of FFP can shorten the preparation time of the wound bed,ease the pain,increase the bacterial clearance rates and the survival rates of the skin graft.Therefore it has a good prospect for clinical application.