中医睡眠调控技术干预慢性失眠的临床研究

Clinical Research on Traditional Chinese Medicine Sleep-regulation Technique in the Treatment of Chronic Insomnia

目的:探究中医睡眠调控技术干预慢性顽固性失眠的效果。方法:选取2017年1月至2017年10月中国中医科学院广安门医院收治的慢性顽固性失眠患者60例作为研究对象,按照随机数字表法分为对照组与观察组,每组30例,观察组在维持原药物治疗方案基础上采用中医睡眠调控技术干预;对照组维持原药物治疗方案不变。疗程为4周。入组前后进行匹兹堡睡眠质量指数(PSQI),及生命质量综合评定问卷(GQOL-74),多导睡眠监测(PSG)检查。结果:治疗4周后,中医睡眠调控技术可明显改善患者PSQI评分,GQOL-74评分各因子和总分。与对照组比较,差异有统计学意义(P<0.05)。中医睡眠调控技术可明显改善患者PSG评分各项指标状态,增加深睡眠期和提高睡眠效率。与对照组比较,差异有统计学意义(P<0.05)。结论:中医睡眠调控技术可以为慢性顽固性失眠患者提供新的选择可能,降低部分患者对西药的依赖性和不良反应,减少慢性顽固性失眠日间症状,提高生命质量,减少复发,应用前景广阔。

Objective:To explore the effect of traditional Chinese medicine(TCM)sleep-regulation technique on chronic intractable insomnia.Methods:A total of 60 patients with chronic intractable insomnia treated in Guang′anmen Hospital of China Academy of Chinese Medical Sciences from January 2017 to October 2017 were selected as the research objects.They were randomly divided into control group and observation group,30 cases in each group.The observation group was intervened by TCM sleep-regulation technique on the basis of the original drug treatment,while the control group maintained the original drug treatment.The course of treatment was 4 weeks.Pittsburgh sleep quality index(PSQI),generic quality of life inventory-74(GQOL-74),and polysomnography(PSG)were examined before and after admission.Results:After 4 weeks of treatment,TCM sleep-regulation technique significantly improved the scores of PSQI and GQOL-74 and the total score(P<0.05).TCM sleep-regulation technique significantly boosted the PSG indexes,increased the deep sleep period and improved sleep efficiency(P<0.05).Conclusion:TCM sleep-regulation technique could provide new choices for patients with chronic intractable insomnia,reduce the dependence of some patients on western medicine and the side effects,alleviate daytime symptoms of chronic intractable insomnia,improve the quality of life,and lower the recurrence,with broad application prospects.