血纤维蛋白原及血清钾和血清镁检测对急性复发性脑梗死患者预后的影响分析

Analysis of the influence of serum fibrinogen, serum potassium and magnesium on the prognosis of patients with acute recurrent cerebral infarction

目的探讨血纤维蛋白原(FIB)、血清钾(K^(+))、血清镁(Mg^(2+))检测对急性复发性脑梗死患者预后的影响。方法选取2018年5月至2020年5月于本院神经内科确诊为急性复发性脑梗死的85例患者作为研究组,另选取本院同期85名体检健康者作为对照组。比较研究组治疗前后及对照组体检当日血浆FIB、血清K^(+)、血清Mg^(2+)水平;治疗28 d后,根据预后情况将研究组分为基本治愈组、显效组、好转组和无变化组,比较各组血浆FIB及血清K^(+)、Mg^(2+)水平。结果治疗前后,研究组血浆FIB水平均明显高于对照组,血清K^(+)、Mg^(2+)水平均明显低于对照组,且研究组治疗后血浆FIB水平低于治疗前,血清K^(+)、Mg^(2+)水平均高于治疗前,差异有统计学意义(P<0.05)。基本治愈组、显效组、好转组血浆FIB水平均低于无变化组,血清K^(+)、Mg^(2+)水平均高于无变化组,差异有统计学意义(P<0.05)。结论急性复发性脑梗死治疗效果与血FIB、K^(+)、Mg^(2+)水平变化密切相关,监测血FIB、K^(+)、Mg^(2+)水平对于评估患者的预后具有重要价值。

Objective To investigate the effects of blood fibrinogen(FIB),serum potassium(K^(+))and serum magnesium(Mg^(2+))on the prognosis of patients with acute recurrent cerebral infarction.Methods 85 patients with acute recurrent cerebral infarction diagnosed in the Department of Neurology of our hospital from May 2018 to May 2020 were selected as the study group,and 85 healthy people in the same period were selected as the control group.The levels of plasma FIB,serum K^(+),Mg^(2+)in the study group before and after treatment and on the day of physical examination in the control group were compared.After 28 d of treatment,the study group was divided into basic cure group,markedly effective group,improved group and unchanged group according to the prognosis.The levels of plasma FIB and serum K^(+),Mg^(2+)in each group were compared.Results Before and after treatment,the levels of plasma FIB in the study group were significantly higher than those in the control group,and the levels of serum K^(+)and Mg^(2+)were significantly lower than those in the control group.After treatment,the levels of plasma FIB in the study group were lower than those before treatment,and the levels of serum K^(+)and Mg^(2+)were higher than those before treatment,and the difference was statistically significant(P<0.05).The plasma FIB level in the basically cured group,the markedly effective group and the improved group were lower than the unchanged group,and the serum K^(+)and Mg^(2+)levels were higher than those in the unchanged group,and the difference was statistically significant(P<0.05).Conclusion The therapeutic effect of acute recurrent cerebral infarction is closely related to the changes of blood FIB,K^(+),Mg^(2+)levels.Monitoring the blood FIB,K^(+),Mg^(2+)levels is of great value in evaluating the prognosis of patients.