膀胱过度活动综合征和肠易激综合征的关系研究进展

Research progress on the relationship of overactive bladder syndrome and irritable bowel syndrome

膀胱过度活动综合征是令世界范围内全年龄段人群困扰的一种下尿路症状综合体,病因及发病机制不清,常常治疗效果不佳。近年来随着对其研究的深入发现膀胱过度活动综合征患者常伴有肠易激等肠道功能性改变,其与肠易激综合征呈现高共病特点。我们将从共病发生、发病机制、治疗三方面探讨膀胱过度活动综合征和肠易激综合征的关系,以期发现膀胱过度活动综合征和肠易激综合征的相似之处,为膀胱过度活动综合征和肠易激综合征的发病机制和治疗提供新的线索和方法。

Overactive bladder syndrome is a complex of lower urinary tract symptoms that disturbs people of all ages worldwide.The etiology and pathogenesis are unclear,and the treatment effect is often poor.In recent years,with the in-depth study of overactive bladder,it has been found that patients with overactive bladder are often accompanied by intestinal functional changes such as irritable bowel,which presents high comorbidities with irritable bowel syndrome.This article will discuss the relationship of overactive bladder and irritable bowel syndrome from three aspects of comorbidities,pathogenesis and treatment,in order to find similarities between overactive bladder and irritable bowel syndrome.It provides new clues and methods for the pathogenesis and treatment of overactive bladder and irritable bowel syndrome.