化痰通络汤治疗中老年急性脑梗死临床观察

Clinical Observation of syndrome differentiation plus or minus treatment of acute cerebral infarction in middle and old aged patients with different subtypes of syndrome

目的探讨化痰通络汤治疗在中老年急性脑梗死患者中的临床应用效果。方法回顾性分析2018年8月—2020年8月120例中老年脑梗死患者的临床资料,根据疾病类型分组。痰瘀阻络组(40例)、风痰瘀阻组(40例)给予化痰通络汤治疗,对照组(40例)采用常规西药治疗。3组患者持续治疗14 d。分别对3组患者治疗总有效率、神经功能(NIHSS)及预后情况进行分析。结果与对照组比较,痰瘀阻络组、风痰瘀阻组治疗总有效率更高(P<0.05);痰瘀阻络组、风痰瘀阻组治疗后NIHSS评分相比对照组明显更低(P<0.05);痰瘀阻络组、风痰瘀阻组与对照组比较,预后良好率更高(P<0.05)。结论根据中老年急性脑梗死患者的辨证类型采用化痰通络汤进行治疗,不仅能够提高患者的临床治疗效果,改善其神经功能,还能在一定程度上改善患者的预后。

Objective To investigate the clinical application effects of JianduanTongluo decoction combined with syndrome differentiation and reduction therapy in different subtypes of middle-aged and elderly patients with acute cerebral infarction.Methods the clinical data of 120middle and old aged patients with cerebral infarction from August 2018 to August 2020 were retrospectively analyzed,and divided according to the type of disease.The phlegm stasis blocking collaterals group(n=40)and the wind phlegm stasis blocking group(n=40)were administered treatmentswithoutantongluo decoction,while the control group(n=40)was treated with conventional Western medicines.Three groups of patients continued treatment for 14 d.The overall response rate,neurological function(NIHSS)and outcome were analyzed in each of the three groups.Results The compared with the control group,the total effective rate of treatment was higher in the phlegm stasis blocking collaterals type group and the wind phlegm stasis blocking group(P<0.05);The NIHSS scores after treatment in the phlegm stasis blocking collaterals type group and wind phlegm stasis blocking group were significantly lower compared with the control group(P<0.05);The good prognosis rate was higher in the phlegm stasis blocking collaterals type group and the wind phlegm stasis blocking group compared with the control group(P<0.05).Conclusion according to the syndrome differentiation type of middle-aged and elderly patients with acute cerebral infarction,treatment of them with Huo Tongluo Decoction can not only improve the clinical treatment effect of patients,improve their neurological function,but also improve the prognosis of patients to some extent.