基于数据挖掘分析马培之及贺季衡临证治疗胃痛医案的用药规律

Medication rule analysis of Ma Peizhi and He Jiheng in treating clinical medical records of stomach pain based on data mining

目的基于数据挖掘分析马培之及贺季衡临证治疗胃痛医案的用药规律。方法收集整理《孟河马培之医案论精要》《孟河四家医案医话集》《贺季衡医案》《指禅医案》中有关马培之及贺季衡诊治胃痛的临床医案,运用Medcase数据处理平台,通过频数分析、关联分析、聚类分析数据挖掘方法对其处方进行分析。结果本研究共收集126诊次,其中马培之医案44诊次,贺季衡医案82诊次。马培之医案涉及病理因素15种、治法治则33种、药物96种。解析出6项药对,1项角药,3组新处方。贺季衡医案涉及病理因素35种、治法治则20种、药物119种。解析出7项药对,2项角药,3组新处方。结论马培之擅长根据胃痛发病过程中病机的转化规律,灵活调整治疗原则。贺季衡重视气逆对胃痛发病的影响,常以通降气逆为主治疗胃痛。

Objective To analyze medication rule of Ma Peizhi and He Jiheng in treating clinical medical records of stomach pain based on data mining.Methods The clinical medical records about Ma Peizhi and He Jiheng in the diagnosis and treatment of stomach pain were collected from Meng He Ma Peizhi Medical Records,The Collection of Medical Records and Sayings from Four Doctors in Meng He,He Jiheng Medical Records and Zhi Chan Medical Records.Their prescription was analyzed by Medcase data processing platform through frequency analysis,association analysis,cluster analysis data mining method.Results A total of 126 times were collected in this study.Ma Peizhi medical records were 44 times and He Jiheng medical records were 82 times.Fifteen kinds of pathological factors,33 kinds of treatment principles,and 96 kinds of drugs involved in Ma Peizhi medical records,six kinds of drug pairs,one kind of three-group-drugs and three new prescriptions were analyzed.Thirty-five kinds of pathological factors,20 kinds of treatment principles,119 kinds of drugs involved in He Jiheng medical records,seven kinds of drug pairs,two kinds of three-group-drugs and three new prescriptions were analyzed.Conclusion Ma Peizhi is good at flexibly adjusting the treatment principles according to the transformation law of pathogenesis in the process of stomach pain.He Jiheng is attaching importance to the influence of qi inversion on the incidence of stomach pain,and often treating stomach pain mainly by dredging and reducing qi inversion.