摘要
目的使用5秒泪液分泌测量法测定7~14岁正常儿童泪液分泌量并探讨其应用价值。设计诊断试验。研究对象北京爱尔英智眼科医院行视力筛查的7~14岁正常儿童49例(98眼)。方法对符合入组标准的儿童行5秒泪液分泌测量法测定其泪液分泌量并进行统计学分析。Bland-Altman法行两次测量结果的一致性检验。主要指标泪液分泌测量值,Bland-Altman 95%一致性界限、组内相关系数(ICC)。结果49例98眼泪液测定均值为(3.71±2.36)mm,不同眼别(右眼3.69±2.10 mm、左眼3.73±1.98 mm)、性别(男性3.79±2.16 mm、女性3.55±2.06 mm)及年龄组(7~10岁组3.94±2.23 mm;11~14岁组3.31±1.73 mm)间差异均无统计学意义。两次测量的一致性较好,右眼差值的均值为-0.061,Bland-Altman 95%一致性界限为-4.10~-3.98,ICC为0.763。结论5秒泪液分泌测量法可快速评估儿童泪液分泌量,其可重复性好。
Objective To measure the amount of aged 7-14 years normal children’s tear secretion by 5 second tear secretion measurement method and study its application value.Design Diagnostic test.Participants 49 subjects of aged 7-14 years normal children from Beijing Aier-Intech Eye Hospital were included.Methods All subjects underwent 5-second tear secretion measurement and the data was analyzed statistically.The consistency of two measurement results were tested by Bland-Altman method.Main Outcome Measures The amount of tear secretion,Bland Altman 95%consistency limit,intraclass correlation coefficient(ICC).Results The mean value of 98 eyes was 3.71±2.36 mm.There was no significant difference between right and left eye groups(right eye 3.69±2.10 mm,left eye 3.73±1.98 mm),male and female groups(male 3.79±2.16 mm,female 3.55±2.06 mm),and different age groups(3.94±2.23 mm in 7-10 year old group,3.31±1.73 mm in 11-14 years old group).The consistency of the two measurements are good.The mean value of right eye difference was-0.061,the 95%consistency limit of Bland Altman was-4.10~-3.98,and ICC was 0.763.Conclusions The 5-second tear secretion measurement method can quickly assess the amount of children's tear secretion function,which has high repeatability in children.
作者
刘畅
范春雷
甄妮
孙旭光
Liu Chang;Fan Chunlei;Zhen Ni;Sun Xuguang(Beijing Aier-Intech Eye Hospital,Beijing 100021,China;Aier Corneal Institute,Beijing 100021,China;Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology&Visual Science,Beijing 100730,China)
出处
《眼科》
CAS
2022年第4期301-304,共4页
Ophthalmology in China
关键词
泪液分泌测量
儿童
measurement of tear secretion
children