中国临床重要真菌监测的工作进展

Progress of Clinical Important Fungi Surveillance in China

近年来,随着我国免疫缺陷患者数量的不断增多,侵袭性真菌病的发生率逐年上升,对患者的健康造成了严重威胁。我国缺乏大规模真菌监测数据,临床多以经验性治疗为主,这可能给患者带来不必要的药物暴露和治疗失败风险。在此背景下,2009年北京协和医院牵头成立中国医院侵袭性真菌病监测网(CHIF-NET),2019年国家卫生健康委组建了全国真菌病监测网(CFDSS)。从不同角度逐步形成了覆盖全国各个层次的真菌监测网络,为临床侵袭性真菌病治疗提供参考。基于此,本文回顾了近几年中国临床重要真菌监测的工作进展。

In recent years,with the increasing number of patients with immune deficiency in China,the incidence of invasive mycosis is increasing year by year,which poses a serious threat to patients’lives.Due to the lack of large-scale fungal surveillance data in China,clinical treatment is mainly based on empirical treatment,which may cause unnecessary drug exposure and treatment failure risk to patients.In this context,Peking Union Medical College Hospitalled the establishment of the China Hospital Invasive Fungal Surveillance Net(CHIF-NET)in 2009,and the National Health Commission set up the China Fungal Disease Surveillance System(CFDSS)in 2019.A fungal monitoring network covering all levels of the country has been gradually formed from different angles to provide references for the treatment of invasive fungal diseases in clinical practice.Based on this,this article reviews the progress in the surveillance of clinically important fungi in China in recent years.