代谢相关脂肪性肝病的发病机制及其与肠道真菌群关系的研究进展

Research progress on the pathogenesis of metabolic-associated fatty liver disease and its relationship with intestinal fungal community

代谢相关脂肪性肝病(MAFLD)对人类健康所构成的威胁不容忽视,现代医学关于MAFLD的发病机制的探讨较多,该文回顾了MAFLD的发病机制及其与肠道真菌群的关系,并讨论了肠道真菌群可能影响疾病进展的机制。控制肠道真菌群的策略可能被开发用于治疗或预防肝脏疾病。

The threat of metabolic-associated fatty liver disease(MAFLD)to human health cannot be ignored.There are many discussions about the pathogenesis of MAFLD in modern medicine.In this paper,we review the pathogenesis of MAFLD and its relationship with intestinal fungal community,and discuss the mechanisms by which the intestinal fungal community may influence the disease progression.Strategies to control the intestinal fungal community may be developed to treat or prevent liver disease.