肠道-器官轴的研究进展

Research progress on the gut-organ axis

肠道通过神经、免疫、内分泌通路与多个器官相互作用,这种作用关系被称为肠道-器官轴。肠道微生物在肠道-器官轴中发挥了重要作用。基于这一理论,我们可以通过靶向肠道-器官轴来治疗肠道和多种相关器官的疾病。本文总结了肠-脑轴、肠-肝轴、肠-肺轴、肠-心轴、肠-皮轴、肠-脂肪轴的研究进展。

The gut interacts with multiple organs via neural,immune and endocrine pathways,which is called the gut-organ axis.And gut microbiota plays an important role in the gut-organ axis.Based on this theory,we can treat diseases about the intestine and associated organs by targeting the gut-organ axis.This article reviewed the research progress of the gut-brain axis,the gut-liver axis,the gut-lung axis,the gut-heart axis,the gut-skin axis and the gut-adipose axis.