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阿卡波糖对急性心肌梗死合并糖耐量异常病人心功能及心肌损伤标志物的影响 被引量:3

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摘要 目的观察阿卡波糖对急性心肌梗死合并糖耐量异常病人心功能及心肌损伤标志物的影响。方法选取2018年6月—2020年6月于我院就诊的急性心肌梗死合并糖耐量异常病人110例,按随机数字表法将病人分为观察组和对照组,各55例。在常规治疗基础上,观察组给予阿卡波糖治疗,比较两组治疗前后心功能相关指标、纽约心脏病协会(NYHA)心功能分级、心肌损伤标志物、体质指数和糖耐量情况。结果与治疗前比较,观察组和对照组治疗后左室射血分数(LVEF)升高(P<0.05),左室舒张末期内径(LVEDD)、N末端脑钠肽前体(NT-proBNP)水平、肌酸激酶同工酶(CK-MB)、肌酸激酶(CK)及心肌钙蛋白I(cTnI)、2 h糖耐量试验和体质指数降低(P<0.05);治疗后,观察组LVEF高于对照组(P<0.05),LVEDD、NT-proBNP、CK-MB、CK及cTnI水平、2 h糖耐量试验和体质指数低于对照组(P<0.05)。观察组NYHA心功能分级改善率为89.61%,高于对照组的68.80%,差异有统计学意义(P<0.05)。结论阿卡波糖可有效改善急性心肌梗死合并糖耐量异常病人心功能,减轻心肌损伤,降低体质指数,并改善糖耐量异常。
出处 《中西医结合心脑血管病杂志》 2022年第16期2992-2995,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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