基于数据挖掘的针灸治疗类风湿关节炎取穴规律探析

Analysis of acupoint selection rules of acupuncture and moxibustion in the treatment of rheumatoid arthritis based on data mining

目的总结分析针灸治疗类风湿关节炎的取穴规律,为针灸治疗类风湿关节炎临床与科研提供参考。方法采用计算机检索的方法在中国知网、万方数据库、维普数据库,收集1996年1月至2021年1月针灸治疗类风湿关节炎的临床文献,利用Microsoft Excel 2016进行频次分析,通过SPSS Modeler 18.0、SPSS Statistics 22.0进行关联规则、复杂网络和聚类分析。结果检索文献1588篇,最终纳入225篇文献,包含225个针灸处方,涉及134个穴位,腧穴使用总频次3345;使用频数前三的穴位为足三里、阳陵泉、曲池。出现频次≥40的高频穴位有30个,合计频次2332,占总频次的69.7%;使用频数前三的穴位组合为阳陵泉-足三里、足三里-曲池、曲池-阳陵泉,出现频次>70的穴位组合有26组;选穴涉及十二正经、任督二脉及经外奇穴,穴位选取多来自阳经(2357次,72.34%),其中膀胱经被选用最多(575次,17.65%),其应用腧穴种类也最多(27次,20.45%),其次为经外奇穴,胃经,胆经和督脉;对频次≥40的腧穴制作穴位关联网络图并进行关联规则分析,针刺治疗类风湿关节炎的主要穴位组合为“足三里-三阴交-外关”;通过聚类分析得到5个聚类集群。结论针灸治疗类风湿性关节炎的取穴规律:多选用足太阳膀胱经、经外奇穴、足阳明胃经、足少阳胆经和督脉;主要穴位组合为足三里-三阴交-外关。

Objective To summarize and analyze the acupoint selection rules of acupuncture and moxibustion in the treatment of rheumatoid arthritis,and to provide reference for clinical and scientific research of acupuncture and moxibustion in the treatment of rheumatoid arthritis.Methods Clinical literatures on acupuncture and moxibustion in the treatment of rheumatoid arthritis were collected from CNKI,Wanfang database,and VIP database from January 1996 to January 2021 by computer retrieval method.Microsoft Excel 2016 was used for frequency analysis,and SPSS Modeler18.0 and SPSS Statistics 22.0 were used for association rule,complex network,and cluster analysis.Results A total of1588 literatures were searched,and 225 literatures were finally included,including 225 acupuncture and moxibustion prescriptions,involving 134 acupoints,with a total frequency of 3345.The three most frequently used acupoints were zúsānlǐ,yánglíngquán and qūchí.There were 30 high-frequency acupoints with frequency≥40,with a total frequency of 2332,accounting for 69.7%of the total frequency.The top three acupoint combinations in frequency were yánglíngquán-zúsānlǐ,zúsānlǐ-qūchíand qūchí-yánglíngquán,and 26 acupoint combinations with frequency>70.The selection of acupoints involved twelve regular channels,conception channel and governor channel,and extra ordinary point,and the acupoints were mostly from yang channel(2357 times,72.34%),among which bladder channel was the most selected(575 times,17.65%),and the types of acupoints applied were the most(27 times,20.45%),followed by extra ordinary point,the stomach channel,the gallbladder channel and governor channel.The association network diagram of acupoints with frequency≥40 was made and association rules were analyzed.The main acupoint combination of acupuncture and moxibustion for rheumatoid arthritis was“zúsānlǐ-sānyīnjiāo-wàiguān”.Five clusters were obtained by cluster analysis.Conclusion The acupoint selection rules of acupuncture and moxibustion for rheumatoid arthritis are as follows:the bladder channel of foot-taiyang,extra ordinary point,the stomach channel of foot-yangming,the gallbladder channel of foot-shaoyang and governor channel are more used.The main acupoint combination is zúsānlǐ-sānyīnjiāo-wàiguān.