基于数据挖掘的针灸治疗广泛性焦虑症临床经穴规律研究

Research on the regularity of clinical meridians and points of acupuncture treating generalized anxiety disorder based on data mining

目的通过数据挖掘针灸治疗广泛性焦虑症(GAD)的临床经穴,分析腧穴配伍规律。方法收集中国知网、维普网、万方数据库、PubMed、SinoMed自2001年1月至2021年8月针灸治疗GAD的文献,对临床数据整理分析经穴配伍规律。结果针灸治疗GAD腧穴多归于督脉、肝经、膀胱经;头面颈项、下肢部腧穴最常用;特定穴排序为交会穴、原穴、腧穴;关联规则显示神门-百会-内关相关性最高,百会-三阴交-四神聪提升度最高;聚类分析得出针灸治疗GAD精神症状主穴为百会、印堂、四神聪、风池、神门、内关、三阴交,针灸治疗GAD躯体症状主穴为膻中、丰隆、神庭、中脘、水沟、上星、足三里。结论针灸治疗GAD在整体观念辨证论治理论下,远近取穴为原则、上下配穴、重用特定穴为特点,组方规律采用脏腑辨证、对症相结合,挖掘奇穴治疗GAD的效果,为今后针灸研究提供思路和参考及避免风险获得更高的安全性。

Objective To analysis compatibility law of acupoints,by data mining the clinical acupoints of acupuncture and moxibustion in the treatment of generalized anxiety disorder(GAD).Methods Literatures on acupuncture treatment of GAD from January 2001 to August 2021 from CNKI,VIP,Wanfang Data,PubMed and SinoMed were collected,and clinical data were collated and analyzed for the compatibility rules of acupuncture points.Results Acupuncture and moxibustion treatment of GAD acupoints mainly belong to the governor vessel,liver channel,aladder channel,acupoints on the head,face,neck,and lower extremity were most commonly used;the order of specific points was crossing point,yuan-primary point,acupoints;the association rules show that shénmén-bǎihuì-nèiguān had the highest correlation;cluster analysis showed that the main acupuncture points for treating mental symptoms of GAD were bǎihuì,yìntáng,sìshéncōng,fēngchí,shénmén,nèiguān,and sānyīnjiāo,and the main acupuncture points in the treatment of GAD somatic symptoms were dànzhōng,fēnglóng,shéntíng,zhōngwǎn,shuǐgōu,shàngxīng and zúsānlǐ.Conclusion Acupuncture treatment of GAD in the overall view of syndrome differentiation,the principle of selecting acupoints near and far,the characteristics of specific acupoints,using viscera syndrome differentiation,digging strange acupoints to treat GAD is effective,which provides ideas for acupuncture to obtain safety in the future.