摘要
银屑病关节炎(psoriatic arthritis,Ps A)的临床表现复杂多样,常常在银屑病皮损发生后的5~10年内发生。早期诊断对于改善Ps A的结局非常重要,但是Ps A在国内外的诊断延迟(常常大于2年)现象非常普遍。迄今已有多种筛查工具问世,我们在国内银屑病患者中验证了4种主流筛查问卷的效能,其中早期银屑病关节炎筛查问卷筛查Ps A的敏感性和特异性的综合表现稍优于其他筛查工具;银屑病流行病学筛查工具问卷最为简便,且其综合表现也尚可。对所有银屑病患者常规应用早期银屑病关节炎筛查问卷或银屑病流行病学筛查工具问卷可尽早发现漏诊的Ps A患者。
Clinical manifestations of psoriatic arthritis(Ps A)are diversity and usually presented 5-10 years after the onset of skin psoriasis.Early diagnosis of Ps A iscritical for the better prognosis.Unfortunately,diagnostic delay(usually>2 years)of Ps A isvery common in domestic and abroad.Several questionnaires have been developed for screening possible Ps A until now.We have validated the performances of 4 major screening tools in Chinese patients with psoriasis.Among them,the Early Arthritis for Psoriatic Patients(EARP)questionnaire has the best balanced sensitivity and specificity,and the psoriasis epidemiology screening tool questionnaire(PEST)is the simplest one with acceptable performance.Routinely screen of psoriasis with EARP or PEST questionnaire is recommended in order to identify Ps A patients with EARP early.
作者
戴生明
Dai Shengming(Department of Rheumatology and Immunology,Shanghai Jiaotong University Affiliated Sixth People's Hospital,Shanghai 200233,China)
出处
《中国医学前沿杂志(电子版)》
2022年第8期1-5,I0001,共6页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
银屑病
银屑病关节炎
早期诊断
筛查
问卷
Psoriasis
Psoriatic arthritis
Early diagnosis
Screening
Questionnaire