药学服务干预对2型糖尿病患者药物治疗的效果分析

Analysis of the Effect of Pharmaceutical Service Intervention on Drug Treatment in Patients with Type 2 Diabetes Mellitus

目的:观察药学服务对药物治疗的2型糖尿病患者的干预效果。方法:选取2021年3月-2022年3月同济大学附属杨浦医院收治的100例2型糖尿病患者作为研究对象,随机分为对照组和观察组,各50例。两组患者均采用药物治疗,在此基础上,对照组采用常规干预,观察组采用药学服务干预。对比两组患者用药现状、空腹血糖、餐后2 h血糖、糖化血红蛋白水平、糖化血红蛋白达标率、6个月内低血糖事件发生率。结果:两组患者的用药种类比较,差异无统计学意义(P>0.05);观察组患者的空腹血糖、餐后2 h血糖和糖化血红蛋白水平均低于对照组,差异有统计学意义(P<0.05);观察组空腹血糖、餐后2 h血糖及糖化血红蛋白达标率均高于对照组,低血糖事件发生率低于对照组,差异有统计学意义(P<0.05)。结论:在2型糖尿病患者的治疗中,以口服降糖药物的方式为主,给予患者药学服务干预,能改善患者的血糖水平,降低用药风险,值得在临床推广。

Objective:To observe the intervention effect of pharmaceutical service on drug-treated patients with type 2 diabetes mellitus.Methods:From March 2021 to March 2022,100 patients with type 2 diabetes who were admitted to Yangpu Hospital Affiliated to Tongji University were selected as the research subjects.They were randomly divided into control group and observation group,50 cases in each group.Both groups were treated with drugs,on this basis,the control group was treated with routine intervention,and the observation group was treated with pharmaceutical service intervention.The medication status,fasting blood glucose,2 h postprandial blood glucose,glycosylated hemoglobin level and compliance rate,and incidence of hypoglycemia within 6 months were compared between the two groups.Results:There was no significant difference in the types of drugs between the two groups(P>0.05).The levels of fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The rates of fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin in the observation group were higher than those in the control group,and the incidence of hypoglycemia was lower than that in the control group,with statistically significant differences(P<0.05).Conclusion:In the treatment of patients with type 2 diabetes,taking oral hypoglycemic drugs as the main method and giving patients pharmaceutical service intervention can improve the blood glucose level of patients and reduce the risk of drug use,which is worthy of clinical promotion.