急性酒精中毒患者应用醒脑静辅助治疗的临床效果观察

Observation of Clinical Effect of Adjuvant Therapy of Xingnaojing in Patients with Acute Alcoholism

目的:探讨急性酒精中毒患者应用醒脑静辅助治疗的临床效果。方法:选取2019年3月-2021年6月北京四季青医院收治的70例急性酒精中毒患者作为研究对象,按照随机数字表法将其分为两组,各35例。对照组采取常规治疗,观察组加用醒脑静辅助治疗,比较两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05);观察组清醒时间、症状消失时间、住院时间均短于对照组,差异有统计学意义(P<0.05);治疗后,观察组谷草转氨酶、谷丙转氨酶、谷氨酰转移酶、肿瘤坏死因子、白介素、C反应蛋白均低于对照组,差异有统计学意义(P<0.05)。结论:对急性酒精中毒患者实施醒脑静辅助治疗效果较好,可显著改善其临床症状,临床应用安全性高。

Objective:To investigate the clinical effect of adjuvant therapy of Xingnaojing in patients with acute alcoholism.Methods:A total of 70 patients with acute alcoholism who were admitted to Beijing Sijiqing Hospital from March 2019 to June 2021 were selected as the research subjects.They were divided into two groups according to the random number table method,each with 35 cases.The control group received conventional treatment,and the observation group received adjuvant therapy of Xingnaojing.The treatment effects of the two groups were compared.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05);the incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05);the awake time,symptom disappearance time,and hospital stay in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of aspartate aminotransferase,alanine aminotransferase,glutamyl transferase,tumor necrosis factor,interleukin,and C-reactive protein in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:Xingnaojing adjuvant therapy for patients with acute alcoholism has a good effect,can significantly improve their clinical symptoms,and its clinical application is safe.