摘要
AIM:To determine how green tea and catechins can affect intraocular pressure(IOP)changes.METHODS:Totally 43 young volunteers were included in the study.The experiment was held between noon and 2 p.m.Two extracts—green tea and epigallocatechin gallate(EGCG,400 mg capsules)and placebo(400 mg capsules)were used in the study.Participants were divided into three groups.Green tea extract group(GT group)had 17 subjects,EGCG extract group 17 subjects,control(placebo)group 9 subjects.IOP was measured with the Icare tonometer before and 30 min,1,1.5,2 h after the consumption of each extract and placebo.Results were analyzed using the IBM SPSS program.Statistical confidence level P<0.05.RESULTS:The most significant reduction of IOP from the beginning of the experiment was measured after 2 h in GT group(left 2.18±3.19 mm Hg,P=0.012;right 2.59±1.97 mm Hg,P<0.000)and after 1 h in EGCG extract group(left 2.41±2.98 mm Hg,P<0.004;right 1.94±1.98 mm Hg,P<0.001).In control group no significant changes were measured.CONCLUSION:People who have increased IOP or risk factors for glaucoma development,could benefit from drinking green tea or its concentrated extracts in moderate doses.
