巴曲酶治疗突发性耳聋的疗效观察

Therapeutic effect of batroxase on sudden deafness

目的 探讨巴曲酶在突发性耳聋临床治疗中的应用疗效。方法 选取我院2019年9月-2020年9月期间收治的80例突发性耳聋患者作为研究对象,分为治疗组(巴曲酶+基础治疗)和对照组(基础治疗)各40例,观察两组患者的治疗效果。结果 治疗组患者的治疗有效率(72.50%>55.00%,χ^(2)=4.507)高于对照组(P<0.05),治疗组患者在治疗后的纯音听阈水平[(56.55±3.02)dB<(35.16±3.18)dB,t=3.764]、纤维蛋白原水平[(3.17±0.65)g/L<(4.29±0.86)g/L,t=6.571]低于对照组(P<0.05),治疗组患者的耳鸣症状消失时间[(6.39±1.47)d<(8.91±1.38)d,t=7.905]、眩晕症状消失时间[(6.05±1.26)d<(8.91±1.28)d,t=10.071]比对照组更短(P<0.05)。结论 在突发性耳聋的临床治疗中,巴曲酶的应用疗效显著,可以有效改善患者的听力水平。

Objective To explore the clinical efficacy of batroxase in the treatment of sudden deafness.Methods A total of 80 patients with sudden deafness admitted to our hospital from October 2019 to March 2021 were selected as the research object,and were divided into the treatment group (batroxase + basic treatment) and the control group (basic treatment),40 cases in each group,and the therapeutic effect of the two groups was observed.Results The effective rate of the treatment group (72.50%>55.00%,χ^(2)=4.507) was higher than that of the control group (P < 0.05).The pure tone threshold level of the treatment group after treatment[(32.55±3.02) dB < (35.16±3.18) dB,t=3.764]and fibrinogen levels[(3.17±0.65) g/L < (4.29±0.86) g/L,t=6.571]were lower than those in the control group (P < 0.05).The disappearance time of tinnitus symptom in the treatment group[(6.39±1.47) d < (8.91±1.38) d,t=7.905]and the disappearance time of vertigo symptom[(6.05±1.26) d < (8.91±1.28) d,t=10.071]was shorter than that of control group (P < 0.05).Conclusion In the clinical treatment of sudden deafness,batroxase can improve the hearing level of patients effectively.