肉芽肿性乳腺炎的激素治疗进展

Glucocorticoid management of granulomatous mastitis:A review of literature

肉芽肿性乳腺炎(granulomatous mastitis,GLM)是非哺乳期乳腺炎之一,好发于有哺乳史的经产女性,是一种良性的肉芽肿性病变。近年来,该病的发病率逐渐升高,临床上越来越常见。因该病病程漫长,病情容易反复、经久不愈,给患者的身心造成了较大的伤害。糖皮质激素是治疗GLM最常用的药物之一,但目前临床上没有统一的用药标准,使用剂量及疗程各有所异。因激素的用法、用量错误,在治疗过程中不仅延误了患者的病情,还引起了诸多的副作用。本文作者大量地阅读了近年来国内外关于激素治疗GLM的相关文献,详细阐述了激素治疗GLM的最新进展,以供临床参考。

Granulomatous mastitis(GLM)is one of the non-lactation mastitis.It is a benign granulomatous disease that occurs in women with a history of lactation.In recent years,the disease is becoming common in clinic,with a gradually increasing incidence.Its long course as well as recurrences has done great harms to the patient physically and psychologically.Glucocorticoid is one of the most commonly administered drugs for GLM,but there is no prescription standard clinically at present so that the dosage and course of treatment vary.Even worse,the wrong usage and dosage of glucocorticoid may not only delay the patient′s condition,but also cause many side effects.In this paper,the authors have reviewed a large number of domestic and foreign literatures on glucocorticoid treatment of GLM in recent years,and elaborated the latest progress for clinical reference.