新型冠状病毒感染者密切接触者的密切接触者感染风险分析

Analysis on infection risk in secondary close contacts of COVID-19 patients

目的研究新型冠状病毒(新冠病毒)感染者密切接触者(密接)的密接(次密接)感染率,评估新冠病毒感染者次密接的感染风险。方法采用前瞻性研究的方法,对进入集中隔离医学观察时且采样检测核酸结果为阴性的密接(与指示病例有明确的暴露时间)及其次密接进行持续医学观察,收集新冠病毒感染者密接和次密接的动态核酸检测结果,评估密接和次密接的感染风险。结果追踪调查了符合纳入条件的密接4533例,14例密接转归为新冠病毒感染者,感染率为0.31%。共追踪了次密接4201例,均未发生后续感染。结论密接进入集中隔离医学观察时采样检测核酸结果为阴性,该次密接无感染风险。

Objective To study the infection rate of secondary close contacts of COVID-19 patients,and assess the infection risk in the contacts.Methods COVID-19 patients'close contacts(with a clear exposure time to index case)with negative nucleic acid test results and secondary close contacts were surveyed in continuous isolation and medical observation in this prospective study.The dynamic nucleic acid test results of the close contacts and secondary contacts of COVID-19 patients were collected to assess their risk of infection.Results A total of 4533 close contacts were surveyed,in whom 14 were confirmed as COVID-19 patients with overall secondary attack rate of 0.31%,and 4201 secondary contacts were tracked,in whom no subsequent infections occurred.Conclusion Close contacts of COVID-19 patients entered in centralized isolation for medical observation with negative nucleic acid tese results,the secondary close contacts of COVID-19 patients have no risk of infection.