转运铁蛋白和血清铁蛋白与老年前列腺良性增生患者术后康复的相关性分析

目的探讨转运铁蛋白(TF)和血清铁蛋白(SF)与老年前列腺良性增生(BPH)患者术后康复的相关性.方法235例老年BPH患者行TF和SF检测,分为TF低值组、SF低值组、对照组,并在手术前后对所有患者行IPSS评分、术后6个月行QOL评分分析.结果TF低值组术前、术后1、3、6个月IPSS评分(28.3±3.1)分、(15.0±2.8)分、(9.0±2.7)分、(7.5±1.2)分,术后6个月QOL评分(2.1±1.3)分;SF低值组术前、术后1、3、6个月IPSS评分(30.5±3.0)分、(16.0±3.2)分、(14.0±2.9)分、(9.5±0.8)分,术后6个月QOL评分(2.8±2.1)分,均高于对照组(24.2±4.1)分、(11.5±1.8)分、(5.5±1.5)分、(4.6±0.8)分(1.0±0.9)差异有统计学意义(P<0.05).≥75岁患者术后6个月对照组、TF低值、SF低值IPSS、QOL为(5.1±1.9)分、(8.4±2.5)分、(10.1±1.5)分、(2.4±1.4)分,高于≤74岁组(4.2±4.6)分、(6.1±2.9)分、(8.1±2.0)分、(1.5±2.2)分,差异有统计学意义(P<0.05).TF低值、SF低值与术后1、3、6个月IPSS评分存在相关性(P<0.01).结论转运铁蛋白和血清铁蛋白含量低于正常值后,前列腺增生症状相对明显,并影响老年前列腺良性增生患者手术后的康复.

Objective To study the correlations between transferrin(TF),serum ferritin(SF)and postoperative recovery of elderly patients with benign prostatic hyperplasia(BPH).Methods Test TF and SF in 235 patients with BPH.Divide them into TF low-value group,SF low-value group,and control group based on the results.Analyze IPSS before and after surgery and QOL 6 months after surgery for all patients.Results In the TF low-value group,IPSS before surgery,1 month after surgery,3 months after surgery,and 6 months after surgery were 28.3±3.1,15±2.8,9.0±2.7 and 7.5±1.2,respectively,and QOL 6 months after surgery was 2.1±1.3.In the SF low-value group,IPSS before surgery,1 month after surgery,3 months after surgery,and 6 months after surgery were 30.5±3.0,16.0±3.2,14.0±2.9 and 9.5±0.8,respectively,and QOL 6 months after surgery was 2.8±2.1.The results of both group were higher than those of control group,in which IPSS before surgery,1 month after surgery,3 months after surgery,and 6 months after surgery were 24.2±4.1,11.5±1.8,5.5±1.5 and 4.6±0.8,respectively,and QOL 6 months after surgery was 1.0±0.9(P<0.05).In patients≥75 years old,IPSS of control group,TF low-value group and SF low-value group were 5.1±1.9,8.4±2.5 and 10.1±1.5,respectively,and QOL was 2.4±1.4.These were higher compared with patients≤74 years old,in which IPSS were 4.2±4.6,6.1±2.9 and 8.1±2.0 respectively and QOL was 1.5±2.2.There were significant differences between these two age groups(P<0.05).The IPSS 1 month after surgery,3 months after surgery,and 6 months after surgery were correlated in both TF low-value group and SF low-value group(P<0.01).Conclusion When the contents of transfer ferritin and serum ferritin are lower than normal,the symptoms of prostate hyperplasia are relatively obvious,and it affects the recovery of elderly patients with benign prostatic hyperplasia after surgery.