心房颤动高功率短时程量化消融的研究进展

Advances in high-power short-duration quantitative radiofrequency ablation of atrial fibrillation

肺静脉隔离是心房颤动消融治疗的基石。既往消融方式复杂耗时且远期复发率较高。消融指数和损伤指数为综合了消融功率、时间和压力的量化参数,其指导下的高功率短时程射频消融能显著缩短手术、消融时长,损伤效果更为持久。本综述旨在简述心房颤动射频消融治疗现况及主要挑战,并评估量化参数指导下高功率短时程消融策略的临床疗效和安全性。

Pulmonary vein isolation is the cornerstone of atrial fibrillation ablation therapy.However,conventional ablation therapy is complicated and time-consuming,with disappointing long-term recurrence clinical outcomes.There are two surrogate endpoints in which contain complex mathematical formulas.Ablation index and lesion size index are the quantitative parameters corporating ablation power,contact force,and duration of ablation delivery.Both can effectively guide the clinician to achieve transmural lesions with high-power short-duration radiofrequency ablation,significantly shortening the duration of surgery and ablation.The purpose of this review is to summarize the current status and main challenges of radiofrequency ablation for atrial fibrillation and to evaluate the clinical efficacy and safety of the high-power short-duration ablation strategy under the guidance of quantitative parameters.