卡前列甲酯栓联合催产素预防剖宫产产后出血的疗效观察

Efficacy Observation of Carboprost Methyl Suppository Combined with Oxytocin in Prevention of Postpartum Hemorrhage after Cesarean Section

目的:探讨卡前列甲酯栓联合催产素预防剖宫产产后出血的临床疗效。方法:选取2019年10月-2020年10月锦州医科大学附属第三医院收治的50例剖宫产产妇作为研究对象,依据给药类型不同,将其分为对照组与试验组,各25例。对照组给予卡前列甲酯栓预防产后出血,试验组在对照组基础上加用催产素。比较两组产妇术中出血量、术后24 h出血量、不良反应发生率、第三产程时间及满意度。结果:试验组术中、术后24 h出血量均少于对照组,差异有统计学意义(P<0.05)。试验组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。试验组产妇第三产程时间短于对照组,满意度评分高于对照组,差异有统计学意义(P<0.05)。结论:利用卡前列甲酯栓联合催产素可以有效预防产后出血的发生,有效减少了产妇的术中出血量以及24 h出血量,减少不良反应的发生,值得临床推广。

Objective:To explore the clinical efficacy of carboprost methyl suppository combined with oxytocin in the prevention of postpartum hemorrhage after cesarean section.Methods:Fifty women of cesarean section in the Third Affiliated Hospital of Jinzhou Medical University from October 2019 to October 2020 were selected as the study subjects.According to the different types of administration,they were divided into control group and experimental group,with 25 cases in each group.The control group was given carboprost methyl suppository to prevent postpartum hemorrhage,while the experimental group was given carboprost methyl suppository combined with oxytocin to prevent postpartum hemorrhage.The intraoperative blood loss,postoperative 24-hour blood loss,incidence of adverse reactions,time of the third stage of labor and satisfaction were compared between the two groups.Results:The amount of bleeding during operation and 24 hours after operation in the experimental group was less than that in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05).The time of the third stage of labor in the experimental group was shorter than that in the control group,and the satisfaction score was higher than that in the control group,with statistically significant difference(P<0.05).Conclusion:The use of carboprost methyl suppository combined with oxytocin can effectively prevent the occurrence of postpartum hemorrhage,effectively reduce the amount of bleeding during operation and 24 hours after operation,reduce the occurrence of adverse reactions,which is worthy of clinical promotion and application.