中成药防治重大慢性病的药物经济学评价体系构建

Construction of the pharmacoeconomic evaluation system of Chinese patent medicine in the prevention and treatment of major chronic diseases

目的 探索构建中成药防治重大慢性病的药物经济学评价体系。方法 分析中成药防治重大慢性病药物经济学评价存在的问题,以问题为导向,探索可用于系统评价中成药防治重大慢性病的药物经济学理论、工具和方法,构建相关药物经济学评价体系。结果与结论 中医药防治重大慢性病有优势,这种独特优势需要在药物经济学评价中得到挖掘、体现和证明。中成药的药物经济学评价近年来获得了一定发展,但是中成药防治重大慢性病优势的药物经济学评价仍存在理论和方法学方面的不足,简单套用化学药的经济学评价指标及技术很难真实、全面地体现中成药的价值。应该围绕中成药药物经济学特有属性,挖掘中成药“治未病”和发挥人体自身调节作用的经济学价值指标,统筹考虑中成药药物经济学在研究设计、研究角度、目标人群、干预措施和对照选择、研究时限、评价方法等方面的特殊性,并通过系统建模、真实世界研究以及建立体现中医药特点的中医生命质量评价量表,全面、综合地反映中成药防治重大慢性病的经济学价值,从而更好地体现中成药防治重大慢性病的优势。

OBJECTIVE To explore the construction of system of pharmacoeconomic evaluation for Chinese patent medicine in preventing and treating major chronic diseases. METHODS The problems in pharmacoeconomic evaluation of Chinese patent medicine for preventing and treating major chronic diseases were analyzed. Based on the problem,the pharmacoeconomic theory,tools and methods that can be used to systematically evaluate the prevention and treatment of major chronic diseases by Chinese patent medicine were explored to build the relevant pharmacoeconomic evaluation system. RESULTS & CONCLUSIONS Traditional Chinese medicine shows the advantages in the prevention and treatment of major chronic diseases. This unique advantage needed to be explored,reflected and proved in the pharmacoeconomic evaluation. The pharmacoeconomic evaluation of Chinese patent medicine had made some progress in recent years. However,there were still deficiencies of theory and methodology in the pharmacoeconomic evaluation for the advantages of Chinese patent medicine in preventing and treating major chronic diseases. It was difficult to truly and comprehensively reflect the value of Chinese patent medicine by simply applying the economic evaluation indicators and technologies of chemical medicine. It is necessary to focus on the unique pharmacoeconomic attributes of Chinese patent medicine,excavate the economic value indicators of Chinese patent medicine for“preventive treatment of disease”and playing the self-regulation role of human body,comprehensively consider the pharmacoeconomic particularity of Chinese patent medicine in respects of research design,research angle,target population,intervention measures and control selection,research time limit and evaluation method,etc. Through the use of system modeling,real-world research and the establishment of Chinese medicinal quality of life scale that reflects the characteristics of TCM,the economic value of Chinese patent medicine in the prevention and treatment of major chronic diseases is reflected comprehensively, so as to reflect the advantage of Chinese patent medicine in preventing and treating major chronic diseases.