红核妇洁洗液联合乳酸菌阴道胶囊治疗霉菌性阴道炎的效果及对阴道分泌物炎症指标、阴道菌群的影响

Effects of Honghe Fujie lotion combined with Lacidophilin vaginal capsules in the treatment of mycotic vaginitis and its influences on inflammatory indexes of vaginal secretions and vaginal flora

目的 探讨红核妇洁洗液联合乳酸菌阴道胶囊治疗霉菌性阴道炎的效果及对阴道分泌物炎症指标、阴道菌群的影响。方法 选取2019年1月至2021年1月我院收治的94例霉菌性阴道炎患者作为研究对象,根据抽签法随机将其分为对照组和观察组,各47例。对照组采用乳酸杆菌阴道胶囊治疗,观察组在对照组基础上联合红核妇洁洗液治疗。比较两组的治疗效果。结果 观察组的治疗总有效率高于对照组(P<0.05)。治疗后,观察组的白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的G~+杆菌、G~+球菌及G~-杆菌菌群检出率低于对照组(P<0.05)。结论 红核妇洁洗液联合乳酸菌阴道胶囊治疗霉菌性阴道炎的效果显著,有利于改善阴道分泌物炎症指标及阴道菌群。

Objective To explore the effects of Honghe Fujie lotion combined with Lacidophilin vaginal capsules in the treatment of mycotic vaginitis and its influences on inflammatory indexes of vaginal secretions and vaginal flora.Methods Ninety-four patients with mycotic vaginitis admitted in our hospital from January 2019 to January 2021 were selected as the research objects.According to the drawing lots method,the patients were randomly divided into control group and observation group,with 47 cases in each group.The control group was treated with Lacidophilin vaginal capsules,and the observation group was treated with Honghe Fujie lotion on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After treatment,the levels of interleukin-2(IL-2),interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the detection rates of G^(+)bacilli,G^(+)cocci and G^(-)bacilli in the observation group were lower than those in the control group(P <0.05).Conclusion Honghe Fujie lotion combined with Lacidophilin vaginal capsules has remarkable effect in the treatment of mycotic vaginitis,which is beneficial to improve the inflammatory indexes of vaginal secretions and vaginal flora.