地佐辛或瑞芬太尼复合丙泊酚在无痛人流术中的麻醉效果比较

Comparison of the anesthetic effects of dezocine or remifentanil combined with propofol in painless artificial abortion

目的 比较地佐辛或瑞芬太尼复合丙泊酚在无痛人流术中的麻醉效果。方法 选取2019年1月至2021年1月本院收治的200例无痛人流术患者作为研究对象,遵循数字随机法将其分为参照组(n=100,瑞芬太尼复合丙泊酚麻醉)和研究组(n=100,地佐辛复合丙泊酚麻醉)。比较两组的体征指标、麻醉效果、不良反应发生情况、丙泊酚用量、麻醉起效时间、术后意识恢复时间、下腹部疼痛程度及麻醉满意度。结果 麻醉前(T_(0))、麻醉2 min后(T_(1))、手术开始时(T_(2))、手术结束时(T_(3))、患者苏醒时(T_(4)),两组的平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO_(2))、舒张压(DBP)、收缩压(SBP)均下降(P<0.05);T_(1)、T_(2)、T_(3)、T_(4)时,研究组的HR、DBP、SBP均高于参照组,差异具有统计学意义(P<0.05)。研究组的麻醉效果优率高于参照组,差异具有统计学意义(P<0.05)。研究组的不良反应总发生率低于参照组(P<0.05)。研究组的丙泊酚用量少于参照组,麻醉起效时间、术后意识恢复时间均短于参照组,差异具有统计学意义(P<0.05)。术后10 min,研究组的轻度疼痛率明显高于参照组,重度疼痛率明显低于参照组(P<0.05)。研究组的麻醉满意度明显高于参照组(P<0.05)。结论 相比于瑞芬太尼复合丙泊酚,地佐辛复合丙泊酚用于无痛人流术中的麻醉效果更佳,对生命体征影响更小,不良反应发生率更低,丙泊酚用量更少,麻醉起效时间及术后意识恢复时间更短,镇痛效果更好,麻醉满意度更高。

Objective To compare the anesthetic effects of dezocine or remifentanil combined with propofol in painless artificial abortion.Methods A total of 200 patients with painless artificial abortion admitted in our hospital from January2019 to January 2021 were selected as the research objects,and the patients were divided into reference group(n=100,remifentanil combined with propofol anesthesia) and study group(n =100,dezocine combined with propofol anesthesia)according to the digital random method.The physical signs indexes,anesthetic effect,adverse reactions,propofol dosage,anesthetic onset time,postoperative consciousness recovery time,lower abdominal pain degree and anesthesia satisfaction were compared between the two groups.Results Before anesthesia(T_(0)),after 2 min of anesthesia(T_(1)),at the beginning of the operation(T_(2)),at the end of the operation(T_(3)),and when the patient wakes up(T_(4)),the mean arterial pressure(MAP),heart rate(HR),oxygen saturation(SpO_(2)),diastolic blood pressure(DBP) and systolic blood pressure(SBP) of the two groups decreased(P<0.05);at T_(1),T_(2),T_(3) and T_(4),the HR,DBP and SBP of the study group were higher than those of the reference group,and the differences were statistically significant(P<0.05).The excellence rate of anesthesia effect of the study group was higher than that of the reference group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the reference group(P<0.05).The dosage of propofol in the study group was less than that in the reference group,the onset time of anesthesia and the recovery time of postoperative consciousness were shorter than those in the reference group,and the differences were statistically significant(P<0.05).At10 min after operation,the mild pain rate in the study group was significantly higher than that in the control group,the severe pain rate was significantly lower than that in the control group(P <0.05).The anesthesia satisfaction of the study group was significantly higher than that of the reference group(P<0.05).Conclusion Compared with remifentanil combined with propofol,dezocine combined with propofol for painless artificial abortion has a better anesthetic effect,with less influence on vital signs,lower incidence of adverse reactions,less dosage of propofol,shorter onset time of anesthesia and recovery time of postoperative consciousness,better analgesic effect and higher anesthesia satisfaction.