夹脊穴温针灸结合循经点穴推拿对腰椎间盘突出症患者腰椎功能、肌电图及β-EP、α1-AGP、TXB_(2)水平的影响

Effects of warm needling moxibustion at Jiaji points combined with acupoint massage along the meridian on lumbar function,electromyography and the levels of β-EP,α1-AGP and TXB_(2) in patients with lumbar disc herniation

目的 探讨夹脊穴温针灸结合循经点穴推拿对腰椎间盘突出症患者腰椎功能、肌电图及β-内啡肽(β-EP)、α1-酸性糖蛋白(α1-AGP)、血栓素B_(2)(TXB_(2))水平的影响。方法 选取2019年10月至2021年5月我院收治的60例腰椎间盘突出症患者为研究对象,根据随机数字表法将其分为对照组与观察组,各30例。对照组采用常规治疗加循经点穴推拿,观察组在对照组基础上开展夹脊穴温针灸治疗。比较两组的治疗效果。结果 观察组的治疗总有效率为96.67%,高于对照组的73.33%,差异具有统计学意义(P<0.05)。治疗后,两组的Lehmann评分均升高,Oswestry功能障碍指数(ODI)、视觉模拟评分法(VAS)评分均降低,且观察组的Lehmann评分高于对照组,ODI、VAS评分低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组左侧平均功率频率(MPF)、右侧MPF、左侧积分肌电值(iEMG)、右侧i EMG均高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的肿瘤坏死因子-α(TNF-α)、基质金属蛋白酶-3(MMP-3)、降钙素原(PCT)水平均低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的血浆β-EP水平高于对照组,血浆α1-AGP、TXB_(2)水平低于对照组,差异具有统计学意义(P<0.05)。结论 夹脊穴温针灸结合循经点穴推拿治疗腰椎间盘突出症可调节炎性因子与β-EP、α1-AGP、TXB_(2)水平,改善患者的腰椎功能,缓解其疼痛程度,提高整体疗效,值得推广。

Objective To explore the effects of warm needling moxibustion at Jiaji points combined with acupoint massage along the meridian on lumbar function,electromyography and the levels of β-endorphin(β-EP),α1-acid glycoprotein(α1-AGP) and thromboxane B_(2)(TXB_(2)) in patients with lumbar disc herniation.Methods A total of 60 patients with lumbar disc herniation admitted in our hospital from October 2019 to May 2021 were selected as the study objects.According to the random number table method,the patients were divided into control group and observation group,with 30cases in each group.The control group was treated with routine treatment and acupoint massage along the meridian,while the observation group was treated with warm needling moxibustion at Jiaji points on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was 96.67%,which was higher than 73.33% in the control group,the difference was statistically significant(P<0.05).After treatment,the Lehmann score of the two groups increased,and the Oswestry Disability Index(ODI) and Visual Analogue Scale(VAS) scores decreased,and the Lehmann score of the observation group was higher than that of the control group,the ODI and VAS scores were lower than those of the control group,and the differences were statistically significant(P<0.05).After treatment,the left mean power frequency(MPF),the right MPF,the left integrated electromyography(iEMG)and the right i EMG in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of tumor necrosis factor-α(TNF-α),matrix metalloproteinase-3(MMP-3) and procalcitonin(PCT) in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the plasma β-EP level of the observation group was higher than that of the control group,and the plasma α1-AGP and TXB_(2)levels were lower than those of the control group,the differences were statistically significant(P<0.05).Conclusion The warm needling moxibustion at Jiaji points combined with acupoint massage along the meridian in the treatment of lumbar disc herniation can adjust the levels of inflammatory factors andβ-EP,α1-AGP,TXB_(2),improve the lumbar function of patients,relieve pain degree and improve the overall curative effect,which is worthy of promotion.