电针治疗小儿抽动障碍肾阴亏损-肝风内动型41例临床观察

Clinical observation on 41 cases of tic disorders in children with kidney-yin consumption and liver-wind stirring type treated by electroacupuncture therapy

目的 观察电针治疗小儿抽动障碍肾阴亏损-肝风内动型的临床疗效。方法 选取2019年1月至2020年12月于浙江中医药大学附属第二医院针灸科住院部治疗的抽动障碍肾阴亏损-肝风内动型患儿78例,按照随机数字表法分为对照组37例和治疗组41例。对照组口服盐酸硫必利片治疗,治疗组予电针治疗,2组均3个月为1个疗程,连续治疗1个疗程后统计疗效。结果 治疗前2组的中医证候积分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组的中医证候积分均较同组治疗前明显降低,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。治疗前2组的耶鲁综合抽动严重程度量表(YGTSS)评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组的YGTSS评分均较同组治疗前明显降低,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。治疗组总有效率为95.12%(39/41),明显高于对照组的67.57%(25/37),2组比较,差异有统计学意义(P<0.05)。对照组不良反应发生率为21.62%(8/37),治疗组为2.44%(1/41),2组比较,差异有统计学意义(P<0.05)。结论 电针治疗小儿抽动障碍肾阴亏损-肝风内动型疗效确切,可明显改善临床症状,降低中医证候积分和YGTSS评分,且不良反应少,值得临床推广应用。

Objective To observe the clinical efficacy of electroacupuncture(EA) therapy for tic disorders in children with kidney-yin consumption and liver-wind stirring type.Methods From January 2019 to December 2020,78 cases of tic disorders in children with kidney-yin consumption and liver-wind stirring type treated in inpatient department of acu-moxibustion department in Second Hospital Affiliated to Zhejiang Chinese Medical University were divided into control group with 37 cases and treatment group with 41 cases according to random number table method.The control group was given oral administration of tiapride hydrochloride tablets,while the treatment group was given EA therapy.Three months constituted 1 course of treatment for both groups,and we kept statistics about the efficacy after continuously treated for 1 course of treatment.Results Before treatment,the difference was not statistically significant in TCM symptom scores between the 2 groups(P>0.05),indicating comparability.After treatment,TCM symptom scores of the 2 groups significantly decreased as compared with the same group before treatment,and the difference was statistically significant(P<0.05),moreover,the decrease was more significant in the treatment group(P<0.05).Before treatment,there was no statistically significant difference in the Yale Global Tic Severity Scale(YGTSS) scores between the 2 groups(P>0.05),indicating comparability;After treatment,the YGTSS scores of the 2 groups significantly decreased as compared with the same group before treatment,and the difference was statistically significant(P<0.05),moreover,the decrease was more significant in the treatment group(P<0.05).The total effective rate was 95.12%(39/41) in the treatment group,which was significantly higher than 67.57%(25/37) in the control group,and the difference was statistically significant between the 2 groups(P<0.05).The incidence of adverse reactions was 21.62%(8/37) in the control group and 2.44%(1/41) in the treatment group,and the difference was statistically significant between the 2 groups(P<0.05).Conclusion It can markedly improve clinical symptoms,reduce TCM symptom scores and the scores of YGTSS with definite efficacy and less adverse reactions to use EA therapy for tic disorders in children with kidney-yin consumption and liver-wind stirring type,which is worthy of clinical promotion and application.