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诊疗一体化超顺磁性氧化铁纳米颗粒用于胰腺癌靶向成像与治疗的研究进展 被引量:1

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摘要 胰腺癌是一种高度恶性肿瘤,多数患者在诊断时已为中晚期甚至已经转移。目前的临床诊断方法难以对胰腺癌进行早期诊断,导致患者整体预后较差。化疗在胰腺癌的治疗中起着至关重要的作用,但在提高生存率方面效果却十分有限。纳米医学的出现为胰腺癌的诊断和治疗提供了新的途径,其中超顺磁性氧化铁纳米颗粒(SPIONs)因其独特的超顺磁性、MRI能力和药物递送能力而受到广泛关注。本文就SPIONs在胰腺癌靶向成像、治疗和诊疗一体化方面的最新研究进展作一述评,并讨论了一些新的治疗策略和未来的发展方向。
出处 《浙江医学》 CAS 2022年第16期1687-1693,共7页 Zhejiang Medical Journal
基金 国家自然科学基金面上项目(82171998) 浙江省自然科学基金项目(LZ22H180002)。
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