Relation of weight change after twenty on subsequent diabetes risk

Objective To explore the association between weight change from age 20 to middle age and diabetes risk.Methods A total of 10 104 residents over 40 years old were recruited in Guangzhou. The final analysis data set was a cohort of 6 272 patients from the REACTION study.Quartile of weight changes from age 20 to middle-age were used as an independent variable to explore its association with newly diagnosed diabetes. Simple and multivariable logistic regression analysis were used to calculate OR and 95%CI.