运动调节代谢综合征患者脂肪因子的研究进展

Research progress of exercise modulates adipokines in patients with metabolic syndrome

代谢综合征是一组多种代谢性疾病的危险因素,包括中心性肥胖、血脂异常、糖代谢紊乱、高血压等在同一个体聚集的临床综合征。代谢综合征的核心成分是脂肪组织,脂肪组织除了作为能量储存器官外,还可以被视为一个动态的、复杂的内分泌器官,产生和分泌多种脂肪因子。运动对人体的新陈代谢是有益的,但运动作用于代谢综合征的机制还不完全清楚,可能与能量消耗和脂肪因子的变化有关。因此,该文选择一些代谢综合征相关经典脂肪因子,对运动调节脂肪因子可能的机制进行综述,为治疗胰岛素抵抗和肥胖提供新的思路。

Metabolic syndrome is a group of risk factors for a variety of metabolic diseases,including central obesity,dyslipidemia,glucose metabolism disorders,hypertension,and other clinical syndromes clustered in the same individual.The core component for metabolic syndrome is adipose tissue,besides its role as an energy storage organ,adipose tissue can be viewed as a dynamic and complex endocrine organ,which produces and secretes several adipokines.Exercise is beneficial to human metabolism,although the mechanisms underlying exercise in metabolic syndrome are not fully understood,changes in energy expenditure and adipokines might be involved.Therefore,this article selects some classic adipokines in metabolic syndrome to review the possible mechanisms of exercise modulating adipokines,so as to provide new ideas for the treatment of insulin resistance and obesity.