彭建中教授运用肾病组方治疗慢性肾脏病的临床观察

Clinical observation of Prof.Peng Jianzhong’s application of nephrotic formulas in the treatment of chronic kidney disease

目的观察彭建中教授运用肾病组方治疗慢性肾脏病的临床疗效。方法选取慢性肾脏病患者374例,予中药肾病组方治疗,不限制西医基础治疗,包括控制饮食、血糖、血压等。观察治疗前后血肌酐(Cr)、尿素氮(BUN)、尿酸(UA)、肾小球滤过率(GFR)、甘油三酯(TG)、总胆固醇(TC)、24 h尿蛋白定量、尿蛋白、尿隐血的变化。结果治疗后Cr、UA较治疗前均降低(P<0.05),GFR较治疗前升高(P<0.05),BUN治疗前后比较差异无统计学意义(P>0.05)。TG、TC治疗前后比较差异均无统计学意义(P>0.05)。治疗后24 h尿蛋白定量较治疗前降低(P<0.05)。治疗后尿蛋白情况优于治疗前(P<0.05),治疗后尿隐血情况优于治疗前(P<0.05)。结论彭建中教授运用肾病组方治疗慢性肾脏病具有较好的临床疗效。

Objective To observe the clinical efficacy of nephrotic formulas by Professor Peng Jianzhong for chronic kidney disease.Methods A total of 374 patients with chronic kidney disease were selected and treated with nephropathy formulas,without limiting the basic treatment of Western medicine,including diet,blood glucose and blood pressure.The changes in creatinine(Cr),uric acid(UA),urea nitrogen(BUN),glomerular filtration rate(GFR),triglyceride(TG),total cholesterol(TC),24-hour urine total protein quantification,urinary protein and urinary occult blood were observed before and after treatment.Results After treatment,Cr and UA decreased(P<0.05)and GFR increased(P<0.05),and there was no significant difference before and after BUN treatment(P>0.05).There was no significant difference in TG and TC before and after treatment(P>0.05).The 24-hour urine total protein quantification was lower after treatment than before treatment(P<0.05).The urinary protein after treatment was better than that before treatment(P<0.05),and the urinary occult blood after treatment was better than that before treatment(P<0.05).Conclusions The nephrotic formulas that Professor Peng Jianzhong uses to treat chronic kidney disease have a good clinical effect.