腹腔镜手术与经腹直肠癌根治术治疗大肠癌的临床疗效比较

Comparison of Clinical Efficacy Between Laparoscopic and Transabdominal Radical Resection for Colorectal Cancer

目的:评价大肠癌患者应用腹腔镜手术及经腹直肠癌根治术的治疗效果。方法:选取2018年4月~2019年7月本院66例大肠癌患者,根据随机数字表法将患者分为两组,各33例,参考组采用术式为经腹直肠癌根治术,研究组采用术式为腹腔镜手术,对两组手术相关指标及术后肿瘤病灶转移情况进行对比。结果:通过对两组患者手术相关指标进行统计,结果显示,研究组手术操作时间为(123.23±13.25)min、术中失血量为(123.23±13.25)mL、术后排气时间为(2.35±0.49)d、术后进食时间为(5.12±0.43)d、住院时间为(7.45±2.13)d,均低于对照组的(159.14±12.56)min、(143.25±21.23)mL、(4.87±0.56)d、(7.32±0.52)d、(14.25±2.09)d,两组有显著差异(P<0.05)。参考组与研究组患者术后并发症总发生率分别为24.24%、6.06%,相比于参考组,研究组总发生率显著更低(P<0.05)。研究组术后肿瘤病灶转移率为9.09%,低于参考组的27.27%,两组有显著差异(P<0.05)。结论:与经腹直肠癌根治术相比,腹腔镜手术在大肠癌治疗中的应用,可有效减轻对患者造成的创伤,有利于患者术后机体功能的尽早恢复,同时可有效降低术后肿瘤病灶的转移,疗效可靠。

Objective:To evaluate the therapeutic effect of laparoscopic surgery and transabdominal radical resection of rectal cancer in patients with colorectal cancer.Methods:From April 2018 to July 2019,66 patients with colorectal cancer in our hospital were selected,and the patients were divided into two groups according to the random number table method,with 33 cases in each group.The reference group used the surgical method as radical resection of rectal cancer,and the study group used The surgical procedure was laparoscopic surgery,and the relative indexes of the two groups of surgery and the postoperative tumor metastasis were compared.Results:Through statistics of the operation-related indicators of the two groups of patients,the results showed that the operation time of the study group was(123.23±13.25)min,the intraoperative blood loss was(123.23±13.25)mL,and the postoperative exhaust time was(2.35±0.49)d.The postoperative eating time was(5.12±0.43)d and the hospitalization time was(7.45±2.13)d,which were all lower than the control group’s(159.14±12.56)min,(143.25±21.23)mL,(4.87±0.56)d,(7.32±0.52)d,(14.25±2.09)d,there was a significant difference between the two groups(P<0.05).The total incidence of postoperative complications in the reference group and the study group were 24.24%and 6.06%,respectively.Compared with the reference group,the total incidence of the study group was significantly lower(P<0.05).The postoperative tumor metastasis rate in the study group was 9.09%,which was lower than 27.27%in the reference group.There was a significant difference between the two groups(P<0.05).Conclusion:Compared with transabdominal radical resection of rectal cancer,the application of laparoscopic surgery in the treatment of colorectal cancer can effectively reduce the trauma to the patient,which is beneficial to the early recovery of the patient’s body function after surgery,and it can effectively reduce the postoperative tumor lesions.The curative effect is reliable.