摘要
事件相关电位(ERPs)在慢性意识障碍(pDOC)患者的意识评估和预后预测中发挥重要作用,尤其是N100、失匹配负波、P300、N400等成分。ERPs试验范式的改进、对ERPs成分的脑源定位分析及脑网络研究、ERPs与其他技术的结合等是pDOC评估中的研究热点。本文现围绕上述方向的应用研究进展综述如下,以期为后续临床研究提供参考。
Event-related potentials(ERPs),especially N100,mismatch negative,P300 and N400,play important roles in the evaluation of consciousness and prognoses of patients with prolonged disorders of consciousness(pDOC).The improvement of ERPs experimental paradigm,analysis of brain origin and brain network of ERPs components,and combination of ERPs with other techniques are the research hotspots in pDOC evaluation.This article reviews the recent advance in the above directions as follows,in order to provide reference for subsequent clinical research.
作者
王衍刚
尹绍雅
王宏图
Wang Yan'gang;Yin Shaoya;Wang Hongtu(Clinical College of Neurology,Neurosurgery and Neurorehabilitation,Tianjin Medical University,Tianjin 300350,China;Department of Neurosurgery,Huanhu Hospital,Tianjin University,Tianjin Neurosurgical Institute,Tianjin 300350,China;Department of Rehabilitation Medicine,Huanhu Hospital,Tianjin University,Tianjin 300350,China;Department of Neurosurgery,Jiaozuo People's Hospital)
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2022年第8期853-857,共5页
Chinese Journal of Neuromedicine
基金
天津市自然科学基金面上项目(20JCYBJC00930)。
关键词
慢性意识障碍
事件相关电位
失匹配负波
P300
评估
Prolonged disorder of consciousness
Event-related potential
Mismatch negative
P300
Evaluation
