纤维支气管镜灌洗在儿童肺炎支原体肺炎治疗中的效果研究

Effect of Fiberoptic Bronchoscopy Lavage in the Treatment of Children with Myco⁃plasma Pneumoniae Pneumonia

目的探讨纤维支气管镜灌洗在儿童肺炎支原体肺炎(MPP)治疗中的临床效果。方法选取2019年1—12月100例揭阳市人民医院收治的MPP患儿,随机数表法分为观察组和对照组,每组50例。两组患儿入院后均给予常规检查,在此基础上对照组患儿给予甲泼尼龙琥珀酸钠进行常规治疗,观察组患儿在对照组的基础上联合纤维支气管镜灌洗进行治疗。两组患儿均治疗2周并持续观察2周,比较两组患儿治疗期间的临床体征、不良反应发生情况以及治疗后的临床效果。结果观察组患儿治疗后的临床总有效率为94.00%显著低于对照组的76.00%,差异有统计学意义(χ^(2)=6.353,P<0.05);对照组患儿咳嗽好转时间、应用糖皮质激素时间、肺部体征改善时间、啰音消失时间、体温正常时间相比于观察组均显然更长,差异有统计学意义(P<0.001);治疗期间,两组患儿不良反应发生情况经比较差异无统计学意义(P>0.05)。结论纤维支气管镜灌洗治疗儿童MPP可以促进患儿临床体征的改善,效果显著,且期间无明显不良反应,整体安全性高。

Objective To investigate the clinical effect of fiberoptic bronchoscopy lavage in the treatment of children with Mycoplasma pneu⁃moniae pneumonia(MPP).Methods A total of 100 children with MPP who were admitted to Jieyang People's Hospital from January to Decem⁃ber 2019 were selected and randomly divided into an observation group and a control group,50 cases in each group.Both groups of children were given routine examination after admission.On this basis,the children in the control group were given methylprednisolone sodium succi⁃nate for routine treatment,and the children in the observation group were treated with fiberoptic bronchoscopy lavage on the basis of the con⁃trol group.The two groups of children were treated for 2 weeks and continued to be observed for 2 weeks.The clinical signs,adverse reactions and clinical effects after treatment were compared between the two groups.Results After treatment,the clinical total effective rate of the obser⁃vation group was 94.00%,which was significantly lower than that of the control group,which was 76.00%,and the difference was statistically significant(χ^(2)=6.353,P<0.05).The time,the improvement time of pulmonary signs,the disappearance time of rales,and the time of normal body temperature in the control group were significantly longer than those in the observation group,and the difference was statistically signifi⁃cant(P<0.001).During the treatment,the incidence of adverse reactions in the two groups was compared,the difference was not statistically significant(P>0.05).Conclusion Fiberoptic bronchoscopy lavage in the treatment of children with MPP can improve the clinical signs of children,and the effect is significant,and there are no obvious adverse reactions during the period,and the overall safety is high.