摘要
目的研究聚多卡醇泡沫硬化剂联合负压封闭引流术(vacuum sealing drainage,VSD)治疗下肢静脉性溃疡的临床疗效。方法回顾性分析2017年1月—2019年12月深圳市龙华区中心医院烧伤整形血管外科共收治109例下肢静脉溃疡患者,根据手术方式分为硬化剂组(采用聚多卡醇泡沫硬化剂+凡士林)52例,VSD组(聚多卡醇泡沫硬化剂+VSD)57例。比较两组患者术前及术后30、90、180 d静脉临床严重程度评分表(VCSS)评分及溃疡面积。结果术后30、90、180 dVCSS评分均较术前降低,且VSD组VCSS评分(7.42±3.17)分、(4.51±2.45)分、(2.86±1.53)分明显低于硬化剂组,差异有统计学意义(t=5.176、6.608、3.482,P<0.05);术前、术后7 d,两组溃疡面积比较,差异无统计学意义(P>0.05),术后30、90 d,硬化剂组溃疡面积多于VSD组,差异有统计学意义(P<0.05)。结论聚多卡醇泡沫硬化剂联合VSD治疗下肢静脉性溃疡安全性高、效果佳,具有临床价值。
Objective To study the clinical effect of podocanol foam sclerosing agent combined with negative pressure closure drainage(VSD)in the treatment of venous lower extremity ulcer.Methods From January 2017 to December 2019,a total of 109 patients with venous lower ex⁃tremity ulcers in Department of Burn and Plastic Vascular Surgery of Longhua District Central Hospital of Shenzhen were retrospectively analyzed.According to different surgical methods,they were divided into:sclerosing agent group(using polidocanol foam sclerosing agent+vaseline),52 cases,and VSD group(polydocanol foam sclerosing agent+VSD),57 cases.The Venous Clinical Severity Scale(VCSS)evalua⁃tion and ulcer area were compared between the two groups before operation and at 30 d,90 d,and 180 d after operation.Results The preopera⁃tive VCSS scores at 30 d,90 d,and 180 d after surgery were all lower than those before surgery,and the VCSS scores in the VSD group were(7.42±3.17)points,(4.51±2.45)points,and(2.86±1.53)points,which were significantly lower than those before surgery,and the difference was statistically significant(t=5.176,6.608,3.482,P<0.05).There was no statistically significant difference in the ulcer area between the two groups before and 7 d after operation(P>0.05).At 30 d and 90 d after operation,and the ulcer area in the sclerosant group were more than that in the VSD group,and the difference was statistically significant(P<0.05).Conclusion Podocanol foam sclerosing agent combined with VSD in the treatment of venous lower extremity ulcer has high safety,good effect,and has clinical value.
作者
彭鹏
刘阳
张中强
徐石
PENG Peng;LIU Yang;ZHANG Zhongqiang;XU Shi(Department of Burn and Plastic Vascular Surgery,Longhua District Central Hospital of Shenzhen,Shenzhen,Guangdong Province,518110 China)
出处
《世界复合医学》
2022年第7期157-160,共4页
World Journal of Complex Medicine
基金
深圳市龙华区医疗机构2020年区级科研项目(2020151)。
关键词
慢性下肢静脉疾病
下肢静脉曲张
下肢静脉性溃疡
泡沫硬化剂
负压封闭引流术
Chronic venous disease of lower extremities
Varicose veins of lower extremities
Venous ulcers of lower extremities
Foam scle⁃rosing agent
Negative pressure sealing and drainage