辅助性T细胞分泌的细胞因子在结核病中的作用研究进展

Research progress on role of cytokines secreted by helper T cells in tuberculosis

结核分枝杆菌引起的结核病是一种典型的慢性感染性疾病,我国作为全球结核病负担最重的国家之一,需要加强结核病的消灭工作。结核病与机体细胞免疫功能密切相关,辅助性T细胞(Th)在其中发挥重要作用,具有提高诊断方法准确性,判断病情严重程度,辅助疾病治疗等作用。本文对辅助性T细胞分泌的细胞因子在结核病发展过程中的变化和应用进行阐述,为加强结核病诊断和治疗提供帮助。了解和探索Th细胞分泌的细胞因子在结核病中的作用,对诊断和治疗结核病有很大帮助。

Tuberculosis caused by Mycobacterium tuberculosis is a typical chronic infectious disease. As one of the countries with the heaviest TB burden in the world, China needs to strengthen the eradication of TB. Tuberculosis is closely related to the cellular immune function of the body, and helper T cells play an important role in it, which can improve the accuracy of diagnostic methods, judge the severity of the disease, and assist in the treatment of the disease. In this review, the changes and application of cytokines secreted by helper T cells in the development of tuberculosis are described, which is helpful for strengthening the diagnosis and treatment of tuberculosis. Understanding and exploring the role of cytokines secreted by Th cells in tuberculosis is of great help in the diagnosis and treatment of tuberculosis.