硬膜外分娩镇痛浓度及时机对母婴影响的研究进展

Research progress on the influence of concentration and timing of epidural labor analgesia on mother and infant

近年来,随着人们生活水平的提高,产妇对于无痛分娩的要求也越来越高。现代医学水平的快速发展使各种先进的分娩镇痛方式和镇痛药物不断涌现。其中硬膜外分娩镇痛被认为是目前临床最常用的分娩镇痛方法,可以有效缓解分娩疼痛,但是在镇痛的同时可能会造成产程延长、新生儿窒息以及引起分娩并发症,包括发热、产后出血、尿潴留等,且镇痛时机、浓度、给药模式等方面各研究结果不尽相同。因此,本文针对硬膜外分娩镇痛的用药浓度、时机、不良反应对母婴影响的研究进展作一综述,旨在为临床探讨硬膜外分娩镇痛给药策略提供参考依据。

In recent years,with the improvement of people′s living standards,parturients have higher and higher requirements for painless delivery.With the rapid development of modern medicine,a variety of advanced labor analgesia methods and analgesic drugs continue to emerge.Among them,epidural labor analgesia is considered to be the most commonly used method of labor analgesia,which can effectively relieve labor pain.however,analgesia may cause prolonged labor,neonatal asphyxia and delivery complications including fever,postpartum hemorrhage,urinary retention and so on.Therefore,this paper reviews the research progress on the effect of epidural analgesia concentration,timing and adverse reactions on mothers and infants,in order to provide a reference basis for clinical discussion of delivery analgesia strategies.