家庭肠内营养对胃癌根治术后患者营养状况的影响

Influence of home enteral nutrition on nutritional status in patients after radical gastrectomy

目的探讨家庭肠内营养对胃癌术后患者营养状况的影响。方法选取2018年8月至12月江苏省肿瘤医院行胃癌根治术的115例患者作为研究对象,采用随机数字表法将其分为研究组(47例)和对照组(68例)。研究组接受家庭肠内营养联合常规饮食指导,对照组仅接受常规饮食指导。比较两组的体重、营养指标和免疫指标。结果两组出院30、60 d后的体重均低于出院前,且研究组出院60 d后的体重减少量低于对照组,差异均有统计学意义(P<0.05)。两组出院30 d后的血清总蛋白、血清白蛋白水平低于出院前,差异均有统计学意义(P<0.05)。两组出院30、60 d后的体重比较,差异无统计学意义(P>0.05)。两组出院60 d后的体重、出院30 d后的体重减少量比较,差异无统计学意义(P>0.05)。两组出院30 d后的血清总蛋白、血清白蛋白、血红蛋白水平以及出院30 d后的CD3、CD4、CD8、CD4/CD8水平比较,差异均无统计学意义(P>0.05)。结论家庭肠内营养可维持患者的体重,减少患者的体重丢失,一定程度地改善了患者的营养状况,值得临床推广使用。

Objective To explore the influence of home enteral nutrition on nutritional status in patients after radical gastrectomy.Methods A total of 115 patients undergoing radical gastrectomy from August to December 2018 were selected as the research objects,and they were divided into the study group(47 cases)and the control group(68 cases)according to random number table method.The patients in the study group received home enteral nutrition combined with regular diet education after discharge,while the patients in the control group only received regular diet education after discharge.The changes in body weight,nutritional indexes and immunity indexes were compared.Results The body weight of the two groups at 30 and 60 days after discharge were lower than those before discharge,and the body weight loss of the study group at 60 days after discharge was lower than that of the control group,the differences were statistically significant(P<0.05).The levels of serum total protein and serum albumin in the two groups at 30 days after discharge were lower than those before discharge,the differences were statistically significant(P<0.05).There were no significant differences in the body weight between the two groups at 30 and 60 days after discharge(P>0.05).There were no significant differences in the body weight and the body weight loss between the two group after 60 days of discharge and 30 days of discharge(P>0.05).There were no significant differences in the levels of serum total protein,serum albumin and hemoglobin at 30 days after discharge,as well as the levels of CD3,CD4,CD8 and CD4/CD8 at 30 days after discharge between the two groups(P>0.05).Conclusion Family enteral nutrition can maintain the body weight of patients,reduce the body weight loss of patients,and improve the nutritional status of patients to a certain extent,which is worthy of clinical promotion and application.