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抗体阳性自身免疫性脑炎的临床特征与预后的研究进展 被引量:1

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摘要 自身免疫性脑炎(autoimmune encephalitis,AE)是由一种中枢神经系统(central nervous system,CNS)抗体相关免疫反应引起的脑炎综合征。它是一种罕见的、严重的、但能治疗的自身免疫性疾病,其主要依赖于神经元抗体检测的特异性和敏感性进行确定诊断。根据抗体的分布情况,AE可分为神经元表面抗原阳性(如NMDAR、GABABR、AMPAR、LGI1等)的AE抗体和胞内或核抗原阳性(如Hu、Ma2、GAD等)的AE抗体。由于与潜在恶性肿瘤的密切关系,后者抗体通常称为副肿瘤抗体[1]。
出处 《中风与神经疾病杂志》 CAS 2022年第8期763-766,共4页 Journal of Apoplexy and Nervous Diseases
关键词 自身免疫性脑炎 临床特征 预后 Autoimmune encephalitis Clinical features Prognosis
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