慢性荨麻疹学龄患儿抗过敏治疗依从性的影响因素分析

Analysis of influencing factors of compliance with anti-allergic therapy in school-age children with chronic urticaria

目的探讨慢性荨麻疹学龄患儿抗过敏治疗依从性的情况及相关影响因素。方法2019年8月至2020年8月应用Morisky用药依从性量表及抗过敏治疗依从性调查问卷对广州市越秀区中医医院皮肤科就诊的92例慢性荨麻疹学龄患儿(6~12岁)进行调查,采用logistic回归分析影响慢性荨麻疹学龄患儿抗过敏治疗依从性的相关因素。结果慢性荨麻疹学龄患儿Morisky用药依从性评分<6分(判为依从性差)52例(56.52%),评分≥6分(依从性良好)40例(43.48%)。经logistic回归分析可知,影响慢性荨麻疹学龄患儿抗过敏治疗依从性的主要因素包括家长疾病认知水平、家庭月收入、用药后无效、用药不良反应、未接受过用药指导等,而定期门诊随访是影响慢性荨麻疹学龄患儿抗过敏治疗依从性的保护因素(P<0.05)。结论慢性荨麻疹学龄患儿抗过敏治疗依从性较差,通过加强患儿家长疾病知识宣教及门诊随访,提高家长参与患儿疾病管理的积极性,将有助于提高患儿抗过敏用药依从性。

Objective To investigate the compliance of school-age children with chronic urticaria by anti-allergic therapy and related influencing factors.Methods A total of 92 cases of school-age children with chronic urticaria(6-12 years old)were investigated with Morisky medication compliance scale and anti-allergic treatment compliance questionnaire from August 2019 to August 2020.The influencing factors related to compliance of anti-allergic therapy in school-age children with chronic urticaria were analyzed with logistic regression analysis.Results The Morisky medication compliance score of school-age children with chronic urticaria was less than<6 points(considered as poor compliance)in 52 cases(56.52%),score≥6 points(good compliance)in 40 cases(43.48%).The school-age children with chronic urticaria on anti-allergic treatment included parents’disease awareness,family monthly income,ineffectiveness after medication,adverse drug reactions,and without receiving clinical guidance etc.,and regular outpatient follow-up was a protective factor affecting the compliance of school-age children with chronic urticaria with anti-allergic therapy by logistic regression analysis(P<0.05).Conclusion School-age children with chronic urticaria have poor compliance with anti-allergic treatment.Strengthening the education and outpatient follow-up of the parents’disease knowledge and improving parents’enthusiasm for participating in the management of children’s diseases will help improve the children’s compliance with anti-allergic medications.