摘要
Chronic stress is a consistent sense of feeling pressured and overwhelmed for a long period of time and it has been defi ned as a maladaptive state that is associated with altered hypothalamic pituitary adrenal(HPA)axis.The hyperactivity of the HPA axis is commonly assessed by cortisol levels.Physical activity(PA)and exercise have been demonstrated to regulate cortisol patterns in different healthy study populations,but also in BC patients and survivors.The PA and exercise are related but have distinct concepts that are commonly misused.Nowadays,the regular practice of PA and exercise has been widely recognized as one main strategy to manage chronic stress and its related markers,like cortisol,remains elusive.In the present review,the authors focused on the evidence of the PA and exercise on cortisol patterns of BC patients and survivors.