摘要
植物miR159靶向MYB基因家族在植物的生长发育、新陈代谢、逆境响应及病原防御等多种生理过程中发挥关键作用。植物miR159可以跨界调控哺乳动物的生理功能,如抑制肿瘤生长、改善能量代谢、抗氧化应激、调节机体免疫功能等。阐述了miR159通过调控MYB基因家族参与多种植物营养生长、逆境胁迫、开花和果实发育过程,以及外源性植物miR159跨界调控哺乳动物生理功能和对乳腺癌的调控作用,以期为后续深入研究植物miR159的调控网络以及跨物种调控机制提供参考。
Plant miR159 has been found to play a key role in a variety of physiological processes such as growth and development,metabolism,response to stress,and pathogen defense in plant by targeting MYB gene family.It has also been proved to have a cross-kingdom regulative role in mammalian physiological functions,such as inhibition of tumor growth,improvement of energy metabolism,anti-oxidative stress and regulation of immunity.This paper described the involvement of miR159 in regulation of nutritional growth,response to stress,flowering and fruit development in a variety of plants,and reviewed the cross-kingdom regulative role of exogenous plant miR159 in mammalian physiological functions and breast cancer,in hoping to provide references for the subsequent study on the regulative network and cross-kingdom regulative mechanism of plant miR159.
作者
段红娟
孟桂智
刘宝宝
贾晶莹
马燕芬
马云
蔡小艳
DUAN Hong-juan;MENG Gui-zhi;LIU Bao-bao;JIA Jing-ying;MA Yan-fen;MA Yun;CAI Xiao-yan(School of Agriculture,Ningxia University/Key Laboratory of Ruminant Molecular and Cellular Breeding of Ningxia Hui Autonomous Region,Yinchuan750021,China)
出处
《畜牧与饲料科学》
2022年第5期48-54,60,共8页
Animal Husbandry and Feed Science
基金
国家自然科学基金项目(31960680)
宁夏回族自治区重点研发计划项目(引才专项)(2018BEB04031)
宁夏大学引进人才科研启动费(30900002218)。