基于多种目标进化算法的蛋白质结构预测计算软件的设计与实现

Design and Implementation of A Protein Structure Prediction Software Based on Many-Objective Evolutionary Algorithms

本文采用多种目标进化算法(Many-Object ive Evolut ionary Algori thms,MaOEAs)作为搜索算法来预测蛋白质的结构,并设计一种蛋白质评价工具的Web应用,搭建软件模拟和软件实验测试平台,对蛋白质结构预测结果进行验证比对。该软件采用Python语言构建,支持用户应用各种蛋白质能量函数进行蛋白质预测,能够更直观地分析计算平台预测的蛋白质数据,并能满足不同用户的需求。

In this paper,we use Many-Objective Evolutionary Algorithms(MaOEAs) as a search algorithm to predict protein structures,and design a Web application of protein evaluation tool to build a software simulation and software experimental test platform to verify and compare protein structure prediction results.The software is built in Python language and supports users to apply various protein energy functions for protein prediction,which can analyze the protein data predicted by the computing platform more intuitively and can satisfy users from various industries.