焦虑情绪与Graves病血清学指标的相关性

Correlation between anxiety and serological indexes of Graves disease

目的 分析研究焦虑情绪与Graves病血清学指标的关系。方法 选取2020年10至2021年1月于本院门诊就诊的227例Graves病患者作为研究对象,根据汉密顿焦虑量表(HAMA)评分分组,HAMA评分<14分为对照组(n=172),HAMA评分≥14分为异常组(n=55)。比较两组HAMA评分、游离三碘甲状原胺酸(FT3)、游离甲状腺素(FT4)及血清促甲状腺激素(TSH)水平;分析HAMA分值与血清学指标相关性。结果 异常组HAMA评分、FT3及FT4水平均高于对照组,TSH水平低于对照组(P<0.05)。相关性分析显示HAMA值与FT3及FT4均呈正相关(r>0,P<0.01),与TSH呈负相关(r<0,P<0.05)。结论 在Graves病患者的治疗过程中,应加强和重视心理因素的评估,必要时行抗焦虑治疗。HAMA有助于临床上快速准确地评估Graves病患者的焦虑状态,值得临床应用推广。

Objective To analyze the relationship between anxiety and Graves disease serological indexes.Methods 227 patients with Graves’ disease who visited the outpatient clinic of our hospital from October 2020 to January 2021 were selected as the research subjects,and were grouped according to the Hamilton anxiety scale(HAMA) score,HAMA score0,P<0.05),and negatively correlated with TSH(r<0,P<0.05).Conclusion During the treatment of patients with Graves disease,the evaluation of psychological factors should be strengthened and emphasized,and anti-anxiety treatment should be performed if necessary.HAMA can help to quickly and accurately assess the anxiety state of patients with Graves disease,and it is worthy of clinical application and promotion.